In silico Characterization of Heat Shock Protein HSP27 in Mammals

Dairy animals have a significant role in every country’s agricultural economy. Livestock is the major sub-sector of industry and value dairy products increasing globally. Under pathological circumstances heat shock proteins (HSPs) promote protein repair, folding, refolding misfolded peptides, possible breakdown irreparable proteins. Heat 27 (HSP27) member small family (sHSPs) also called HSPB1. HSP27 crucial regulation progression different types tumors acts as an oncotherapeutic target humans other mammals especially sheep. By using computational tools, detailed silico investigation sequences from sheep has been examined with respect to their structural, functional, expression phylogenetic properties. An extensive study made compare human that tools. However, are closely linked each other. Although vary, structural characteristics functional properties remain same. In this study, hydrophilic average molecular weight 27kDa were discovered both This helps understand economic worth worldwide. phosphorylation predicted anticancer agent. Recent research shows new strategies developed for cancer treatment based on therapy HSP27. will highlight characterization